Clinical Proof – A Scientifically Validated Approach   

10|2025

Proven Effectiveness: NeuroStar® Advanced Therapy has delivered over 7.1 million treatments, benefiting over 195,000 patients across more than 1,100 practices in the U.S. It is recognized as the market leader in clinical practice for depression treatment.

Long-Term Efficacy: NeuroStar has demonstrated long-term effectiveness with established durability for up to 12 months post-treatment. This indicates sustained benefits after the acute treatment phase.

Response and Remission Rates:

83% of patients show a positive response to an acute course of NeuroStar treatment.

62% of patients achieve remission, meaning they would likely not be diagnosed with Major Depressive Disorder (MDD) after treatment.

Low Discontinuation Rate: NeuroStar has a low discontinuation rate of only 5%, highlighting the acceptance and consistency of the treatment.

Large Clinical Database: NeuroStar’s clinical efficacy is supported by the world’s largest depression Outcomes Registry, with data from over 65 clinical studies involving more than 1,900 patients.

Indications for Use:

Adult: NeuroStar is indicated for treating depressive episodes in adult patients with MDD who have not had satisfactory improvement from antidepressants. It can also address comorbid anxiety symptoms and is used as an adjunct for Obsessive-Compulsive Disorder (OCD).

Adolescent: It is also indicated as an adjunct treatment for MDD in adolescents aged 15-21.

Safety and Side Effects:

The most common side effect is temporary pain or discomfort at the treatment site, which usually subsides after the first week.

There is a rare risk of seizures, occurring in less than 0.1% of patients.

NeuroStar is contraindicated for patients with non-removable conductive metal in or near the head and has not been studied in those who have not previously used antidepressant medications.

Commitment to Compliance: Neuronetics emphasizes its commitment to compliance with healthcare regulations and laws, ensuring proper interaction with healthcare providers.

These findings demonstrate that NeuroStar® is a safe and effective alternative for treating depression, with strong clinical support for its response and remission rates, as well as long-term benefits.

At Colorado TMS Services, we can help you overcome your depression and get you back on your way to living a happier, more fulfilling life. Call us today for more information at (720) 671-0533 or visit our website.